![\"Photo](\"https:\/\/people.brandonu.ca\/chenv\/files\/2016\/01\/Photo-on-2014-10-30-at-16.17-2-298x300.jpg\")
<\/h1>\n<\/h1>\nDr. Vincent Chen<\/strong>, BSc, PhD (Assistant Professor) Brandon University Phone: (204) 727-9775 Web: www.chenlab.ca<\/a><\/p>\n <\/p>\n Publications:<\/p>\n 14. S. Chittaranjan, S. Chan, C. Yang, K.C. Yang, V.C. Chen, A. Moradian, M. Firme, J. Song, N. Go, M. Blough, J. Chan, G. Cairncross, S.M. Gorski, G. Morin, S. Yip, M.A. Marra. (2014). Mutations in CIC and IDH1 cooperatively regulate 2-hydroxyglutarate levels and cell clonogenicity<\/a>. Oncotarget, 5(17), 7960-7979.<\/span><\/span><\/p>\n <\/span><\/span>13. V.C. Chen, J.W. Gouw, C.C. Naus, L.J. Foster. (2013) Connexin Multisite Phosphorylation: Mass spectrometry\u2010based Proteomics Fills the Gap<\/a>. BBA \u2013 Biomembranes. 1828(1): 23\u201334. <\/span><\/p>\n <\/span>12. P.R. Gielen, Q. Aftab, N. Ma, V.C. Chen, X. Hong, S. Lozinsky, C.C. Naus, W.-C. Sin (2013) Connexin43 confers Temozolomide resistance in human glioma cells by modulating the mitochondrial apoptosis pathway<\/a>. Neuropharmacology. doi: 10.1016\/j.neuropharm.2013.05.002.<\/span><\/p>\n <\/span>11. V.C. Chen, A.R. Kristensen, L.J. Foster, C.C. Naus. (2012) The Association of Cx43 with E3 Ubiquitin Ligase TRIM21 Reveals a Mechanism for Gap Junction Phosphodegron Control<\/a>. J Proteome Res. 7;11(12):6134-46.<\/span><\/p>\n <\/span>10. C. Lamiche, J. Clarhaut, P.-O. Strale,\u00a0 S. Crespin, N. Pedretti, F.-X. Bernard, C.C. Naus, V.C. Chen, L.J. Foster, N. Defamie, M. Mesnil, F. Debiais, L. Cronier\u00a0 (2012) The gap junction protein Cx43 is involved in the bone-targeted metastatic behavior of human prostate cancer cells<\/a>. Clinical & Experimental Metastasis. 29:111\u2013122.<\/span><\/p>\n <\/span>9. V.C. Chen, G. Sadler, M.E. McComb, H. Perreault, H.W. Duckworth (2011) Characterization of specific binding by mass spectrometry: Associations of E. coli citrate synthase with NADH and 2-azidoATP<\/a>. Int. Journal Mass Spectrometry. 305:238\u2013246.<\/span><\/p>\n <\/span>8. S. Shojania, G.D. Henry, V.C. Chen, T.N. Vo, H. Perreault, J.D. O\u2019Neil (2010) High yield expression and puri\ufb01cation of HIV-1 Tat1-72 for structural studies<\/a>. J. Virology Methods. 164:35-42.<\/span><\/p>\n <\/span>7. V.C. Chen, C.-C. Chou, H.-Y. Hsieh, H. Perreault, K.-H. Khoo (2008). Targeted identification of phosphorylated peptides by Off-line HPLC-MALDI-MS\/MS using LC Retention Time Prediction<\/a>. Journal Mass Spectrometry. 43:1649-58. <\/span><\/p>\n <\/span>6. E. Lattova, V.C. Chen, S. Varma, T. Bezaheh, H. Perreault (2007) Matrix-assisted laser desorption\/ionization on-target method for the investigation of oligosaccharides and glycosylation sites in glycopeptides and glycoproteins. Rapid Communication Mass Spectrometry<\/a>. 21:1644-1650. <\/span><\/p>\n <\/span>5. S. Snovida, V.C. Chen, Perreault, H. (2006) Use of a novel DHB\/aniline MALDI matrix for improved <\/a><\/span>detection and on-target derivatization of glycans. Analytical Chemistry<\/a>. 78:8561-8568. <\/span><\/p>\n <\/span>4. V.C. Chen, X. Li, H. Perreault, J.I. Nagy (2006) Interaction of zonula occludens-1 (ZO-1) with \u03b1-actinin-4: application of functional proteomics for identification of PDZ domain-associated proteins<\/a>. <\/span>Journal Proteome Research. 9:2123-2134. <\/span><\/p>\n <\/span>3. S.I. Snovida, V.C. Chen, O. Krokhin, H. Perreault (2006) Isolation and identification of sialylated glycopeptides from bovine \u03b11-acid glycoprotein by off-line capillary electrophoresis MALDI-TOF mass spectrometry<\/a>. Analytical Chemistry. 78:6556-6563. <\/span><\/p>\n <\/span>2. V.C. Chen, K. Cheng, W. Ens, K.G. Standing, J.I. Nagy, and H. Perreault. (2004) Device for the reverse-phase separation and on-target deposition of peptides incorporating a novel hydrophobic sample <\/a><\/span>barrier for MALDI mass spectrometry<\/a>. Analytical Chemistry. 76:1189-1196.<\/span><\/p>\n Dr. Vincent Chen, BSc, PhD (Assistant Professor) Director, Brandon University Proteomics Centre Department of Chemistry Brandon University Room 4-11, John R.\u00a0 Brodie Science Centre 270 \u2013 18th Street Brandon, Manitoba R7A 6A9 Phone: (204) 727-9775 Fax: (204) 728-7346 Email:\u00a0chenv@brandonu.ca Web: www.chenlab.ca Publications: 14. S. Chittaranjan, S. Chan, C. Yang, K.C. Yang, V.C. Chen, A. 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\nDirector, Brandon University Proteomics Centre<\/a>
\nDepartment of Chemistry<\/p>\n
\nRoom 4-11, John R.\u00a0 Brodie Science Centre
\n270 \u2013 18th Street
\nBrandon, Manitoba
\nR7A 6A9<\/p>\n
\nFax: (204) 728-7346
\nEmail:\u00a0chenv@brandonu.ca<\/a><\/p>\n1. V. Pham, W. Zang, V.C Chen, Whitney, T., Yao, J., Froese, D., Friesen, A.D.,\r\n Diakur, J.M., and Haque, W. (2003) Design and synthesis of novel pyridoxine 5\u2019\r\n-phosphonates as potential anti-ischemic agents<\/a>. Journal of Medicinal Chemistry. 46:3680-3687.<\/span><\/span><\/span><\/pre>\n\u00a0<\/span><\/span><\/span><\/pre>\n","protected":false},"excerpt":{"rendered":"